19 results
diagnosis management differential oncology anemia causes cppd hemeonc hepatology thrombocytopenia algorithm aplastic apml calcium cerebritis cns coagulation comparison deficiency deposition
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
- Nutritional: B12 ... Microangiopathy: DIC, TTP, HUS ... antiphospholipid syndrome ... sequestration: - Cirrhosis ... Diagnosis #Framework #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Low Serum B12 ... • Small Bowel ... Myelodysplastic Syndromes ... Macrocytosis, Target Cells ... Algorithm #Causes #Hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... limb ischemia, bowel ... : • Pathophysiology ... Lysis of tumor cells ... diagnosis #management #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... Puncture, EEG Treatment ... (for secondary APS ... CNS #neurology #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... - Parvovirus B19 ... • Parvovirus B19 ... aplastic anemia Treatment ... Anemia #oncology #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... Release from blast cells ... diagnosis #management #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Nutritional: vitamin B12 ... factor (GCSF) treatments ... marrow studies Treatment ... Immunosuppressive treatment ... #diagnosis #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... Schistocytes, helmet cells ... + Bleeding Treatment ... diagnosis #causes #treatment ... #management #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
primary biliary cirrhosis ... Nephrogenic DI Hematologic ... Cryoglobulinemia (4%-12% ... Adenocarcinoma Treatment ... #Rheumatology #
Etiologies of Vitamin B12 Deficiency • Inadequate intake - Rare but seen in very strict vegans
destruction of parietal cells ... Abnormal small bowel ... insufficiency, blind loops syndromes ... malabsorption syndromes ... differential #diagnosis #hematology
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