15 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Amy Chung, MD, MSc ... Anticoagulants #Medications ... #Pharmacology # ... Pathophysiology ... Mechanisms #DOAC #Hematology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
For most indications ... #management #algorithm ... #pharmacology # ... treatment #medications ... decisionaid #cardiology #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome ... • Reaction to Medications
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... Responsive to Treatment ... Amy Chung, MD, MSc ... Classification #pathophysiology ... #Hematology #Diagnosis
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... INDICATIONS FOR ... glucocorticoid treatment ... Eosinophil #Disorders #Algorithm ... Differential #diagnosis #hematology
ED Opioid Stewardship Algorithm

Opioid Naive vs Opioid Tolerant

1. Patient Specific, Pain Syndrome-Targeted Approach
2. Combinations of Non-Pharmacologic
Opioid Stewardship Algorithm ... Specific, Pain Syndrome-Targeted ... Combinations of Non-Pharmacologic ... Medication Assisted ... Treatment (MAT)
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... organ damage • Treatment ... : • Pathophysiology ... Lysis of tumor cells ... diagnosis #management #hematology
Neurological Side Effects of Antipsychotic Drugs
Acute dystonia - Spasm of muscles of tongue, face, neck, back
variable tremor, mask ... reduction; change medication ... tremor ("rabbit syndrome ... months or years of treatment ... #SideEffects #pharmacology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... - Antithyroid medications ... aplastic anemia Treatment ... Anemia #oncology #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... Release from blast cells ... Renal Failure Treatment