18 results
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
causes development ... Particular CD4+ Th cells ... harmful -> Th Cells ... macrophages, mast cells ... #Immunology #pathophysiology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... Transcellular Shift Into Cells ... into cells: Insulin ... #potassium #low ... #pathophysiology
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Thrombocytosis: cells ... 7) - principal cells ... #Algorithm #causes ... #potassium #high ... #pathophysiology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
40% of patients diagnosed ... maturation of B cells ... from precursor cells ... CD19+) and plasma cells ... #immunology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
increases out of cells ... repolarization CLASS 3 - Potassium ... ++ influx into cells ... Classification #Classes ... #pathophysiology
Pseudohyperkalemia vs Reverse Hyperkalemia

Pseudohyperkalemia and reverse pseudohyperkalemia are both conditions where potassium levels appear falsely elevated.

Pseudohyperkalemia:
This
leaks from cells ... , or red blood cells ... leukemic white cells ... ECG despite high K+ ... #Nephrology #Diagnosis
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... only if no clear cause ... into cells. ... Management #Treatment #potassium ... #nephrology #K
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
- Differential Diagnosis ... smooth muscle cells ... #Differential #Diagnosis ... #Algorithm #Pathophysiology ... #Nephrology #Chloride
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
repolarization CLASS 3 - Potassium ... • MOA: Block K+ ... ++ influx into cells ... Classification #Classes ... #pathophysiology
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... Octaplex + Vitamin K ... = dilated BV = raises ... water leaves brain cells ... #neurology #neurosurgery