27 results
Bell's palsy
There are many different causes of Facial Nerve Palsy. However, the commonest
cause of unilateral facial
Bell's palsy There ... variety known as Bell's ... - Ptosis #Bells ... #Signs #Symptoms ... #Diagnosis
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
yrs old; F>M Signs ... Anemia - Giant cells ... Temporal #Arteritis #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Vasculitis
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
40% of patients diagnosed ... maturation of B cells ... from precursor cells ... CD19+) and plasma cells ... #immunology
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
• Langerhan cells ... removal of these cells ... Livedo Reticularis, Vasculitis ... Manifestations #pathophysiology ... #diagnosis #signs
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
IgA Vasculitis – ... various inflammatory cells ... #HSP #IgA #Vasculitis ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
vascular endothelial cells ... PolyarteritisNodosa #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Vasculitis
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
mutated in all cells ... Retinoblastoma Signs ... Retinoblastoma #pathophysiology ... ophthalmology #diagnosis ... #signs #symptoms
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
B and CD-4+ T cells ... RheumaticFever #pathophysiology ... #diagnosis #signs
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
the mastoid air cells ... and mastoid air cells ... #Mastoiditis #pathophysiology ... #signs #symptoms ... #diagnosis #otology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Microglial cells ... are the immune cells ... between nerve cells ... Lateral #Sclerosis #neurology