32 results
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... - Differential ... Transcellular Shift Into Cells ... imports K+ into cells ... #low #pathophysiology
Causes of Facial Weakness - Differential Diagnosis Algorithm
Forehead Sparing = Central cause
  - Most commonly
Weakness - Differential ... Diagnosis Algorithm ... - Unilateral: Bell's ... #Diagnosis #Algorithm ... #Causes #neurology
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Pathophysiology: ... germinative skin cells ... Causes: 1) Exfoliative ... Skin-homing T-cells ... Nikolsky #Algorithm #Differential
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Diagnosis Algorithm ... Thrombocytosis: cells ... 7) - principal cells ... #causes #potassium ... #high #pathophysiology
Hypophosphatemia - Differential Diagnosis Algorithm
 • Decreased intake/absorption: Starvation, Alcoholism, Malabsorption, Phosphate binder use
 • Redistribution/
Hypophosphatemia - Differential ... Diagnosis Algorithm ... Redistribution/ Shift into cells ... #Diagnosis #Algorithm ... #causes #nephrology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... Reed-Sternberg (RS) Cells ... Lymphocyte - 5% RS cells ... (LP) tumour B cells ... Classification #pathophysiology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophilia, 500-1,500 cells ... Hypereosinophilia, >1,500 cells ... glucocorticoid treatment ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Approach to Hypomagnesemia 

Fractional excretion of magnesium = (urine magnesium x serum creatinine)/ [0.7 (serum magnesium
magnesium into cells ... Hypomagnesemia #algorithm #differential ... #diagnosis #causes ... #nephrology #magnesium
Oxyhemoglobin Dissociation Curve 

Left Shift - decreased unloading of O2 at tissue level (i.e.  increased
stored red blood cells ... Dissociation #Curve #Pathophysiology ... #Right #Shift #Differential ... #Causes #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Activation of CD8 T cells ... Phagocytosis of blood cells ... Drugs, Unknown cause ... Treatment: •