45 results
Causes of Aplastic Anemia

#Aplastic #Anemia #Causes #Pathophysiology #Pathology #Treatment #Management #Differential
Causes of Aplastic ... #Anemia #Causes ... #Pathophysiology ... #Pathology #Treatment ... #Management #Differential
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
old; F>M Signs/Symptoms ... - Normocytic Anemia ... - Giant cells ... Temporal #Arteritis #Pathophysiology ... #Vasculitis
Oxyhemoglobin Dissociation Curve 

Left Shift - decreased unloading of O2 at tissue level (i.e.  increased
stored red blood cells ... - Sickle cell anemia ... Dissociation #Curve #Pathophysiology ... #Right #Shift #Differential ... #Causes #Diagnosis
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
DiabetesB12 deficiency, Uremia ... Guillain-Barre, Vasculitis ... Leah Willis via ... Peripheral #Neuropathy #differential ... #diagnosis #causes
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
workup for specific symptoms ... for secondary causes ... eosinophilia (common causes ... glucocorticoid treatment ... Disorders #Algorithm #Differential
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... and petechiae Causes ... Treatment: ... • Improve the symptoms
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
breath, wasting, anemia ... Psychiatric symptoms ... Loss of teeth Anemia ... , or any other cause ... Treatment:
Suspected Celiac Disease - Diagnosis Algorithm

Celiac disease suspected:
 • Signs and symptoms of celiac disease
 •
• Signs and symptoms ... Iron-deficiency anemia ... unresponsive to treatment ... without discernable cause ... microscopic colitis Differential
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
conjunction with symptoms ... diagnosis and treatment ... Inflammatory causes ... ANCA-associated vasculitides ... #inflammatory #differential
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Out Secondary Causes ... factor (GCSF) treatments ... blood count with differential ... marrow studies Treatment