12 results
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Allergic reaction ... Particular CD4+ Th cells ... harmful -> Th Cells ... macrophages, mast cells ... #Immunology #pathophysiology
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
leading to an allergic ... plasma cells that ... complexes bind to mast cells ... • Inflammatory cells ... #Immunology #pathophysiology
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
surfaces of body cells ... body cell -> B-Cells ... foreign -> B-cells ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... natural killer cells ... Classification #Pathophysiology ... #Allergy #Diagnosis
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
exposure to a likely allergen ... exposure to known allergen ... #Anaphylaxis #pathophysiology ... #immunology #diagnosis
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
- Differential Diagnosis ... Algorithm Increased ... #Differential #Diagnosis ... #Algorithm #causes ... potassium #low #pathophysiology
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Erythroderma - Diagnostic ... Algorithm. ... Pathophysiology: ... #Diagnosis # ... Erythroderma #Nikolsky #Algorithm
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
- Differential Diagnosis ... Algorithm Reactive ... • Acne • Allergy ... Reed-Sternberg Cells ... #Algorithm #Causes
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Hyperkalemia Differential Diagnosis ... Algorithm R/O ... #Differential #Diagnosis ... #Algorithm #causes ... potassium #high #pathophysiology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... Eosinophilia, 500-1,500 cells ... causes are asthma, allergy ... Eosinophil #Disorders #Algorithm ... #Differential #diagnosis