25 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Coagulation Cascade ... #Medications #Pharmacology ... #Pathophysiology ... Mechanisms #DOAC #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
, coagulation disorders ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... or λ), Smudge Cells ... o CML - bcr-able ... o Other bcr-able ... #hematology #Markers
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Summary of Coagulation ... Malignancy, Autoimmune disorders ... EricsMedicalLectures/ #Coagulation ... Deficiencies #Summary #table ... comparison #diagnosis #hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
TTP/HUS, HELLP Syndrome ... Pregnancy (AFLP) Three syndromes ... presents with coagulation ... AFLP #obstetrics #hematology ... #diagnosis #table
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Lymphoproliferative disorders ... adsorption onto cancer cells ... vonWillebrand #Syndrome ... Management #treatment #hematology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
hemorrhage, while under-coagulation ... management #algorithm #pharmacology ... #medications #table ... decisionaid #cardiology #hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Pregnancy Three syndromes ... presents with coagulation ... pregnancy * Severe coagulation ... Obstetrics #OBGyn #Hematology ... Diagnosis #Comparison #Table
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
intravascular coagulation ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... lymphoproliferative disorders ... differential #diagnosis #hematology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... and endothelial cells ... #Coagulation #Cascade ... diagnosis #models #hematology ... #pathophysiology