11 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Coagulation Cascade ... AntiCoagulation #Cascade ... #Medications #Pharmacology ... #Pathophysiology ... Mechanisms #DOAC #Hematology
Beta-Blockers in Cirrhosis
 • Pathophysiology
 • Indications:  Prevention of decompensation, Prevention of first variceal bleeding,
in Cirrhosis • Pathophysiology ... gastropathy • Dosing ... BetaBlockers #Cirrhosis #hepatology ... #management #pharmacology ... #indications #dosing
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation cascade ... During the initiation ... and endothelial cells ... diagnosis #models #hematology ... #pathophysiology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
management #algorithm #pharmacology ... #medications #table ... decisionaid #cardiology #hematology ... #warfarin #dosing
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Pathophysiology: ... germinative skin cells ... Histamine 4) Skin-homing ... T-cells #Diagnosis ... #Dermatology #Rash
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
release from mast cells ... the complement cascade ... #Differential #Pharmacology ... #Pathophysiology
REBEL Review 90: Weight Based 4 Factor PCC Dosing 

#Hematology #Management #Table #4FactorPCC #REBELReview #Pharmacology #Dosing
Based 4 Factor PCC Dosing ... #Hematology ... #Management #Table ... #REBELReview #Pharmacology ... #Dosing #WeightBased
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
with cytotoxic T cells ... natural killer cells ... blood types or during ... Classification #Pathophysiology ... Diagnosis #Reactions #Table
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... Transient K+ efflux moving ... increases out of cells ... Antiarrhythmics #Pharmacology ... Classification #Classes #pathophysiology
Adrenoceptor Actions
α1
 • Vascular smooth muscle - Contraction
 • Genitourinary smooth muscle - Contraction
 • Intestinal
• Pancreatic ß-cells ... juxtaglomerular cells ... receptors #actions #pharmacology ... #pathophysiology ... #comparison #table