20 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Coagulation Cascade ... AntiCoagulation #Cascade ... #Medications #Pharmacology ... #Pathophysiology ... Mechanisms #DOAC #Hematology
Topical drug formulations, comparison and considerations

#pharmacology #table #medications #comparison #drugs #treatment #pharmacotherapy #dermatology
considerations #pharmacology ... #table #medications ... comparison #drugs #treatment ... pharmacotherapy #dermatology
Here is a quick guide on the common direct-acting antivirals (DAAs) for chronic hepatitis C virus
DAAs #Antivirals #table ... #treatment #hcv ... infectiousdisease #hepatology ... HepatitisC #Management #Pharmacology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation cascade ... and endothelial cells ... #Coagulation #Cascade ... diagnosis #models #hematology ... #pathophysiology
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
release from mast cells ... the complement cascade ... #Differential #Pharmacology ... #Pathophysiology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
management #algorithm #pharmacology ... #treatment #medications ... #table #pharmacotherapy ... decisionaid #cardiology #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
(LP) tumour B cells ... Responsive to Treatment ... growth, response to treatment ... Classification #pathophysiology ... #Hematology #Diagnosis
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology ... diagnosis #comparison #table
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... organ damage • Treatment ... Lysis Syndrome: • Pathophysiology ... Lysis of tumor cells ... diagnosis #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Activation of CD8 T cells ... Unknown cause Treatment ... diagnosis #management #treatment ... #summary #rheumatology