9 results
Mechanisms of thiazide diuretic side effects

Dr. Muner Mohamed @MunerMohamed1

#thiazide #diuretic #pharmacology #pathophysiology #sideeffects #adverseeffects #nephrology
#thiazide #diuretic ... #pharmacology # ... pathophysiology ... #sideeffects #adverseeffects ... #nephrology
Pharmacokinetics of commonly used diuretics medications in CKD, Cirrhotic Ascites, and Heart Failure
 • Furosemide
 •
commonly used diuretics ... Spironolactone MCW Nephrology ... #pharmacology # ... Pharmacokinetics #halflife #comparison ... #table
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diuretics and Agents ... Symport (Loop Diuretics ... Tolvaptan) • Treatment ... #Nephrology #Pharmacology ... #Medications #Table
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
: 33% • Treatment ... : No • Treatment ... : Supportive + diuresis ... hematology #diagnosis #comparison ... #table
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Elimination (see Table ... Stabilization Treatments ... Redistribution Treatments ... Drives K+ into cells ... #potassium #nephrology
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
#Hyperkalemia #treatment ... #pharmacology # ... table #comparison ... #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
kidney tubular cells ... Treatment of underlying ... per day until stable ... Loop diuretics for ... #nephrology
Adrenoceptor Actions
α1
 • Vascular smooth muscle - Contraction
 • Genitourinary smooth muscle - Contraction
 • Intestinal
• Pancreatic ß-cells ... juxtaglomerular cells ... receptors #actions #pharmacology ... #pathophysiology ... #comparison #table
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
apical membrane of cells ... with thiazide diuretic ... Rhabdomyolysis Treatment ... Syndrome #diagnosis #nephrology ... #management #pathophysiology