21 results
Management of patients with known or suspected malignant pleural effusion (MPE) - An Official ATS/STS/STR Clinical
Management of patients ... pleural effusion ... goals of assessing lung ... there are any signs ... /symptoms of worsening
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
mutated in all cells ... Retinoblastoma Signs ... Retinoblastoma #pathophysiology ... ophthalmology #diagnosis #signs ... #symptoms
Fat Embolism Syndrome
Trauma to the long bone or pelvis accounts for —9096 of cases. The diagnosis
Trauma to the long ... bone or pelvis ... Pathophysiology ... Syndrome #Diagnosis #Signs ... #Symptoms
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
friction rub audible Lungs ... pain, pleural effusion ... cause interstitial lung ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Malignant Bone Tumors: Pathogenesis of X-ray appearance

 • Metastatic bone tumors (aka. cancerous cells from systemic
Malignant Bone Tumors ... aka. cancerous cells ... • Lung. thvroid ... Signs/Symptoms: ... #BoneTumors #Malignant
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
More Specific Signs ... Less Specific Signs ... Chest x-ray: signs ... bilateral pleural effusions ... acute HF → no signs
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
vascular endothelial cells ... necrotic purpura - Malignant ... PolyarteritisNodosa #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Vasculitis
Scoliosis: Pathogenesis and clinical findings (Cobb Angle > 10 Degrees)

 • Incr Axial rotation of thoracic
volume -> Decr lung ... expansion -> Decr lung ... #Scoliosis #pathophysiology ... msk #diagnosis #signs ... #symptoms
Constrictive Pericarditis on Echocardiogram
A 55-year-old female marathon runner presents to clinic w/ 6-months of worsening breathlessness
ASA, Kussmaul's sign ... edema, and clear lungs ... circumferential pericardial effusion ... Echocardiogram #a4c ... #pocus #clinical
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... Lysis of tumor cells ... TLS #diagnosis #management