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diagnosis management signs syndrome hematology differential neurology oncology algorithm causes endocrinology gastroenterology infections acute classification complications disorders hiv ibs infectiousdiseases
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... changes, stroke symptoms ... Lysis Syndrome: • Pathophysiology ... Lysis of tumor cells
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
(LP) tumour B cells ... pattern of spread, B symptoms ... Responsive to Treatment ... growth, response to treatment ... Classification #pathophysiology
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
old; F>M Signs/Symptoms ... Anemia - Giant cells ... Temporal #Arteritis #Pathophysiology ... Diagnosis #Signs #Symptoms
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary Diagnosis: • Use a positive diagnostic strategy with
last 3 months + symptom ... for diagnosis Treatment ... • Global IBS Symptoms ... intestinal epithelial cells ... gastroenterology #treatment
Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
mutated in all cells ... Retinoblastoma Signs / Symptoms ... Retinoblastoma #pathophysiology ... diagnosis #signs #symptoms
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
workup for specific symptoms ... Eosinophilia, 500-1,500 cells ... Hypereosinophilia, >1,500 cells ... glucocorticoid treatment ... organ-specific signs or symptoms
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
lymphocytes, smudge cells ... Splenomegaly 5) Symptoms ... transformation) Treatment ... Constitutional symptoms ... AIHA, PRCA) • Treatment
Fat Embolism Syndrome Trauma to the long bone or pelvis accounts for —9096 of cases. The diagnosis
the long bone or pelvis ... Pathophysiology ... Diagnosis #Signs #Symptoms
Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
B and CD-4+ T cells ... RheumaticFever #pathophysiology ... diagnosis #signs #symptoms
Thyrotoxic Periodic Paralysis - Illness Script • Epidemiology: Asian men age 20-30 with hyperthyroidism of any
and menses • Pathophysiology ... thyroid hormone • Symptoms ... hours-days duration +/- symptoms ... or high T3 • Treatment
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