21 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... Differential #Diagnosis #Algorithm ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... risk-stratification • Risks: infection ... only curative treatment ... #hematology #oncology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... drug reaction, infection ... Strongyloides infection ... glucocorticoid treatment ... Differential #diagnosis #hematology
Irritable Bowel Syndrome (IBS) - Management
Global IBS Symptoms:
  - Limited trial low FODMAP diet
Irritable Bowel Syndrome ... intestinal epithelial cells ... and Hepatology ... Irritable #Bowel #Syndrome ... #treatment
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary
Diagnosis:
 • Use a positive diagnostic strategy with
Irritable Bowel Syndrome ... for diagnosis Treatment ... intestinal epithelial cells ... and Hepatology ... #treatment
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Differential Diagnosis Algorithm ... Neoplastic / Hematologic ... • Malignancy Infectious ... Pulmonary Disease Neurologic ... Chronic Fatigue Syndrome
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Neutropenia - recurrent infections ... Idiopathic • Infections ... aplastic anemia Treatment ... Anemia #oncology #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
petechiae) • Frequent infections ... • Parvovirus infection ... factor (GCSF) treatments ... marrow studies Treatment ... #diagnosis #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Release from blast cells ... Differential Diagnosis: Infection ... diagnosis #management #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
weeks without infection ... microglobulin Treatment ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... workup #oncology #hematology