22 results
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Pruritus - Generalized ... Differential Diagnosis Algorithm ... Myelodisplastic syndrome ... parasitosis #Pruritus ... #generalized #dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
sweats, bleeding • Pruritis ... • Tumor lysis syndrome ... -> Invade Skin: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... : - CLL cells ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Treatment
Stop offending agents:
 • List as allergies
Eosinophilia and Systemic ... Treatment Stop ... , IVIG etc • Skin ... antihistamine for pruritis ... #dermatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... Allogeneic stem cell ... only curative treatment ... #hematology #oncology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
associated with systemic ... general feeling of ill ... , breast CA - Hematologic ... Treatment: - Systemic ... #oncology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Lymphoma (HCV) • CLL ... Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Pruritus - No Primary ... Skin Lesion - Differential ... Diagnosis Algorithm ... Myelodisplastic syndrome ... #secondary #systemic
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... site in lymphatic system ... with lymphatic system ... Responsive to Treatment ... pathophysiology #Hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... factor (GCSF) treatments ... marrow studies Treatment ... #diagnosis #hematology ... #oncology