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diagnosis management differential chronic cll hemeonc hodgkins lymphocytic lymphoma lysis mds myelodysplastic acute aki algorithm anemia aplastic cancer comparison disorders
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
Classification of ... Tumor Lysis Syndrome ... (TLS) and Treatment ... #TumorLysis #Syndrome ... #management #oncology
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
change disease • Hematologic ... malignancies Treatment ... Interleukin-2) • Tumor ... #AKI #Cancer #Oncology ... Differential #Diagnosis #Classification
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... lymphoma & Acute leukemia ... malignancies Treatments ... #Lysis #Syndrome ... #TLS #oncology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
organ damage • Treatment ... leukapheresis - TLS ... cells releasing ... #TLS #diagnosis ... #management #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... transformation to acute leukemia ... only curative treatment ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
: Granulocytic cells ... develop leukostasis syndrome ... Fibrinolysis & DIC • Tumor ... lysis syndrome: ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
microglobulin Treatment ... • Richter’s Syndrome ... • Sezary syndrome ... diagnosis #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic Leukemia ... • Most common leukemia ... patients with minimal tumor ... lymphocytes, smudge cells ... #oncology #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
involved) • No leukemic ... translocation • Types: Classification ... extranodal) - Tumor ... ALL) • Solid Tumors ... NonHodgkins #comparison #oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
predominant (LP) tumour ... Responsive to Treatment ... Treated Like Acute Leukemias ... Lymphoproliferative #Disorders #Classification ... pathophysiology #Hematology
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