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diagnosis management rheumatology syndrome dermatology differential symptoms workup chronic cll hemeonc leukemia lymphocytic activation agglutinin aplastic arteritis autoinflammatory behcet canimorsus
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
correlations • Purpura ... Connective tissue disease ... #dermpath #dermatology ... #semiology #signs ... lesions #diagnosis #clinical
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Butterfly rash, Vasculitis ... , Purpura, Urticaria ... ) Blood (75%): Anemia ... erythematosus #signs
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group < 5%
Clinical manifestations ... involvement with purpura ... neuropathy Treatment ... with refractory disease ... #Rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
atherosclerotic disease ... most important diseases ... : Strong sign of ... Multinucleated giant cells ... Differential #Diagnosis #Rheumatology
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Management Summary Clinical ... Signs: • hyperCalcemia ... demineralization) • Renal disease ... marrow plasma cells ... Diagnosis #Management #oncology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Somatic) Syndrome Clinical ... Syndrome: • Common Clinical ... thromboembolic disease ... recurrent fevers, vasculitis ... Abnormalities: macrocytic anemia
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
immunophenotype Clinical ... 5) Symptoms of anemia ... chemotherapy for low-risk disease ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... lesions, palpable purpura ... Behcet syndrome (Clinical ... Arthritis, AS Treatment ... diagnosis #management #signs
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Clinical Presentation ... Treatment: ... #oncology #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Fever is the main clinical ... easy bruising to purpura ... (Petechial or purpuric ... with leukopenia, anemia ... Treatment: • Corticosteroids
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