9 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... marrow) -dys- (abnormal ... = funny-shaped cells ... transformation to acute ... #hematology #oncology
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia
Induction: 
 • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate
Consolidation
Standard-Risk Acute ... mercaptopurine, Weekly oral ... Treatment #timeline #oncology ... #pediatrics #peds ... #management
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
- Differential Diagnosis ... neutrophil count < 500 cells ... mm3 • Single oral ... Hyperuricemia • Acute ... #differential #diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Release from blast cells ... • Rare: DAH, acute ... 500 mg QD until normal ... #management #hematology ... #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
syndrome (MDS) (normal ... megakaryocytes and a normal ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
products that define normal ... lymph node biopsy (diagnostic ... Hodgkins #lymphoma #diagnosis ... classification #hematology #oncology ... #management
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary
Chagas disease (American trypanosomiasis) is an infectious
Trypanosomiasis - Diagnosis ... and Management ... weeks incubation Acute ... PCR + 20-90%, normal ... Tests - check Acute
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
malignancy (Especially acute ... Thrombocytopenia - Normal ... - APTT < 1.5 x normal ... #Coagulation #diagnosis ... causes #treatment #management
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... and Management ... tissue: Epithelioid cells ... ), liver (pain/abnormal ... #Management #Signs