19 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
recessive salt-losing ... prevalence of 1- ... thiazide-sensitive sodium-chloride ... H+ secretion → Hypokalemia ... Pathophysiology #nephrology
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
Hyperkalemia Treatment ... 90 minutes) • Sodium ... lactulose (peaks 1- ... LouLectures #Hyperkalemia ... #nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... Bartter syndrome, Gitelman ... #causes #potassium ... #low #nephrology
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
Hyperkalemia: Diagnostic ... algorithm Decreased ... type 2 • Type 1 ... #Hyperkalemia ... #nephrology #potassium
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Differential Diagnosis Algorithm ... acidosis (type 1 ... Bartter's syndrome, Gitelman's ... #causes #nephrology ... #potassium
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
hypokalemic salt-losing ... thiazide-sensitive sodium ... thiazide-sensitive sodium ... (renal potassium ... Syndrome #diagnosis #nephrology
Workup of Hypercalcemia - Differential Diagnosis Algorithm
High or Normal PTH:
 • Hyperparathyroidism: Parathyroid adenoma, Parathyroid hyperplasia,
Workup of Hypercalcemia ... Differential Diagnosis Algorithm ... Intoxication - High 1, ... Differential #Diagnosis #Algorithm ... #Workup #nephrology
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup

Step #1 - Consider the history
Step #2 - Assess
Differential Diagnosis Algorithm ... Diabetes Insipidus Workup ... Step #1 - Consider ... Hypernatremia #Management #Algorithm ... #Sodium #nephrology
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... Diagnosis Algorithm ... Bartter's syndrome, Gitelman's ... #nephrology #causes ... #low #potassium
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Algorithm Before ... treated with IV potassium ... Bartter syndrome, Gitelman ... #diagnosis #Algorithm ... #nephrology #low