11 results
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... increase dose as ... patients sensitive to high ... of aspiration #Potassium ... #pharmacology #table
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... Diagnosis Algorithm ... Gitelman's syndrome #Hypokalemia ... #nephrology #causes ... #low #potassium
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... Syndrome • HTN, High ... #causes #potassium ... #low #nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Algorithm Before ... complications such as ... urinary losses: • High ... consumption • Low ... #nephrology #low
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
intracellular calcium causes ... - Hyperkalemia ( ... high potassium levels ... Because digoxin binds ... (or low potassium
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
130 mEq/L • Potassium ... Is Dangerous in Hyperkalemia ... shift • Saline Causes ... densa receives high ... • Saline May Cause
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... normal volume-based algorithm ... diuresis can be high ... : Hypovolemia, Hypervolemia ... differential #diagnosis #table
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
only if no clear cause ... Elimination (see Table ... acidosis) • Low ... Management #Treatment #potassium ... #nephrology #K
Pragmatic diagnostic algorithm for hypokalemia. 
***Typical presentations: 
 • Vomiting: urine Na/Cl > 1.6, low urine
Pragmatic diagnostic algorithm ... urine Na/Cl > 1.6, low ... urine Na/Cl < 0.7, high ... correcting serum potassium ... #nephrology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
High mortality. ... Hypocalcemia, Hyperkalemia ... Citrate in RBCs binds ... products contain potassium ... Hypothermia: Due to low