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diagnosis nephrology differential hypokalemia pathophysiology pharmacology binders cardiology comparison digoxin hyponatremia hypotonic low management medications physiologic pseudohyperkalemia reverse sodium treatment
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... increase dose as ... patients sensitive to high ... #Binding #Hyperkalemia ... #pharmacology #table
Hyperkalemia Differential Diagnosis Algorithm R/O Pseudo-hyperkalemia: • Possible Lab error! Alwavs Repeat Blood sample! • Leukocytosis, Thrombocytosis:
Diagnosis Algorithm ... Thrombocytosis: cells lyse as ... TTKG should be high ... #causes #potassium ... #high #pathophysiology
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Algorithm Before ... complications such as ... treated with IV potassium ... urinary losses: • High ... #nephrology #low
Digoxin Pharmacology and Pathophysiology 1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
works by directly binding ... intracellular calcium causes ... - Hyperkalemia ( ... high potassium levels ... , in states of hypokalemia
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
only if no clear cause ... Elimination (see Table ... Treatments: • K-Binding ... Management #Treatment #potassium ... #nephrology #K
Pseudohyperkalemia vs Reverse Hyperkalemia Pseudohyperkalemia and reverse pseudohyperkalemia are both conditions where potassium levels appear falsely elevated. Pseudohyperkalemia: This
potassium is high ... Causes: • Seen ... • ECG findings ... K+, consider pseudohyperkalemia ... #Potassium #Nephrology
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... Urine Na+K / serum ... diuresis can be high ... : Hypovolemia, Hypervolemia ... differential #diagnosis #table
Pragmatic diagnostic algorithm for hypokalemia. ***Typical presentations: • Vomiting: urine Na/Cl > 1.6, low urine
Pragmatic diagnostic algorithm ... urine Na/Cl < 0.7, high ... Tubulopathy: urine K/ ... correcting serum potassium ... #nephrology
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