23 results
Seronegative Inflammatory Arthritis - Differential Diagnosis
 • Seronegative Rheumatoid Arthritis 
 • Infectious Arthritis: Viral, Bacterial,
Inflammatory Arthritis - Differential ... Disease: Systemic Lupus ... Crystal Arthropathy: Gout ... #arthritides #Differential ... #Diagnosis #rheumatology
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Homogeneous: Systemic lupus ... disease (MCTD), Drug-induced ... Lupus, Juvenile ... ANA #patterns #rheumatology ... #diagnosis #differential
Lupus Classification
Spontaneous Lupus
 - Cutaneous Lupus Erythematosus (CLE)
 - Systemic Lupus Erythematosus 
Drug-Induced Lupus
 - Drug-Induced
Erythematosus Drug-Induced ... Lupus - Drug-Induced ... (SCLE-DIL) - Drug-Induced ... erythematosus #rheumatology ... #diagnosis #differential
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... (aPL) 30-45% Differential ... Mimickers: Drug-induced ... symptoms #mimickers #differential ... #rheumatology
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement #SLE #rheumatology ... #pharmacology # ... levels #lupus #management
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
HIV viral load Drug-induced ... Anti-retrovirals, Gemcitabine Lupus ... uncommon 5-15% of lupus ... Myopathies #myopathy #differential ... diagnosis #comparison #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... vs SLE Drug Induced ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
disease (MCTD), Drug-induced ... Idiopathic Arthritis, Drug-Induced ... Biliary Cirrhosis, Drug-Induced ... ANA #patterns #rheumatology ... #diagnosis #differential
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
response to the drug ... #management #algorithm ... #pharmacology # ... decisionaid #cardiology #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
usually IgG) (e.g. lupus ... infection) - Drugs ... Extravascular #Causes #differential ... #diagnosis #hematology