12 results
Antiplatelet Drugs and their Actions

- Amy Chung, MD, MSc
@AmyChung

#Antiplatelet #Medications #Pharmacology #Pathophysiology #Drugs #Agents #COX #GIIbIIIa
Drugs and their Actions ... #Medications #Pharmacology ... #Pathophysiology
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
Immune Reactions ... Immunosuppressant #Drugs #Pharmacology ... #Pathophysiology
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Delayed autoimmune reaction ... RheumaticFever #pathophysiology ... signs #symptoms #complications
Gout: Pathogenesis and Clinical Findings
 - Conditions of rapid cell turnover: hemolysis, psoriasis, lymphoproliferative disorders
 -
cascade results in leukocyte ... Hyperuricemia #Pathophysiology ... #Complications
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
constipation • Allergic reaction ... mediated cytotoxic reaction ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Renal Effect of NSAIDs Inhibition of Prostaglandin Synthesis

 - Renal disease, Cardiovascular disease -> Decreased renal
synthesis, leaving actions ... Prostaglandins #Pharmacology ... #Pathophysiology
Pathogenesis of meningitis 

Risk factors for pathogen entry include immunocompromised state (HIV positive, cancer, chemotherapy patients,
which produces the complications ... expression of more leukocyte ... #Meningitis #Pathophysiology
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
to an allergic reaction ... cells recruited Complications ... Allergy #Immunology #pathophysiology
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
disease states Pathophysiology ... A reaction to phagocytosed ... Intracellular (leukocyte
Adrenoceptor Actions
α1
 • Vascular smooth muscle - Contraction
 • Genitourinary smooth muscle - Contraction
 • Intestinal
Adrenoceptor Actions ... adrenergic #receptors #actions ... #pharmacology # ... pathophysiology