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diagnosis causes hematology hyperkalemia management nephrology algorithm high product anesthesia anesthesiology bands basophilia checklist criticalcare druginduced foamed hemolysis hyperthermia leucocytosis
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Basophilia - Differential ... the total white blood ... during an allergic reaction ... Or Inflammatory Reactions ... #Differential #
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Types: • Leukocyte ... Reaction (FNHTR ... proteins on plts, leukocytes ... potassium from
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... the banked donor blood ... proteins on plts, leukocytes ... potassium from ... in transfused blood
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Crush injury • Blood ... • Recent IV potassium ... reaction - Tumor ... Blood transfusion
Evaluation of Leukocytosis: The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages. Include
Leukocytosis: The term 'leukocyte ... eosinophils, & basophils ... part automated differential ... precursor cells to leukocytes ... NEUTROPHILS #WCC #BASOPHILS
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Crush injury • Blood ... • Recent IV potassium ... reaction - Tumor ... Blood transfusion
Hyperkalemia: Diagnostic algorithm Decreased renal potassium excretion • Acute renal failure • Chronic renal failure • Drugs Increased
Decreased renal potassium ... Drugs Increased potassium ... diet • Blood ... transfusion • ... #differential
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... Blast cells - Blood ... blast cells - Blood ... eosinophilia, basophilia ... Intracellular Urate, Potassium
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... AIHA, Cold AIHA, Transfusion ... reactions, Drug-associated ... - Peripheral Blood ... #Hemolysis #Differential
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Benyzlpenicillin, blood ... #hyperkalemia #differential ... pathophysiology #pharmacology ... #potassium #medications
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