12 results
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
hypersensitivity reactions ... lgE causes mast-cell ... reaction, Haemolytic ... recruitment of leucocytes ... hypersensitivity #reactions
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Reactions: • Immune ... Reaction (FNHTR ... Reaction (AHTR) ... Reaction (DHTR) ... #hematology #reactions
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Reactions Immune ... Reaction (FNHTR ... Reaction (AHTR) ... • Allergic reaction ... #hematology #reactions
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
TRALI vs TACO - Transfusion ... Reactions TRALI ... without other cause ... #Reactions #hematology ... #diagnosis #comparison
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
- Differential Diagnosis ... released during an allergic ... reaction or asthma ... Or Inflammatory Reactions ... #causes #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... reaction, Paroxysmal ... reaction • Intrinsic ... #hematology #anemia
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... prosthetic valve • Transfusion ... reactions ex. ... #Differential #Diagnosis ... #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... are asthma, allergy ... , drug reaction, ... #Differential #diagnosis ... #hematology #eosinophilia
Causes of Pseudocellulitis - Differential Diagnosis Framework for Cellulitis Mimics

Cellulitis: Deep skin and subcutaneous fat infection

Pseudo
- Differential Diagnosis ... antibiotics and avoid allergic ... reactions, C. diff ... Pseudocellulitis: • Drug reaction ... #dermatology #skin
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
maintained fever CAUSES ... device • Blood transfusion ... • Allergic reaction ... Anesthesiology #Anesthesia #Checklist ... #Diagnosis #Management