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diagnosis lupus differential oncology systemic treatment classification disease leukemia signs symptoms workup causes chronic criteria lymphocytic nephrology renal thrombocytopenia acidosis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... - infiltrates (anemia ... • Tumor lysis syndrome ... lymphocytic lymphoma (SLL ... #Leukemia #Hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
(SLE) Clinical ... Demyelinating Syndrome ... thrombosis and/or blood-brain ... #SLE #CNS #neurology ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Suspect: Clinical ... Clinical Features ... edema, active urine ... lymphopenia, low PLT • Anemia ... #Diagnosis #Rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Demyelinating syndromes ... (75%): Anemia ( ... #systemic #erythematosus ... symptoms #diagnosis #rheumatology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Criteria CLINICAL ... SEROSITIS - RENAL - NEUROLOGIC ... #Diagnosis #Rheumatology ... #SLE #Lupus #Erythematosus
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... proportion of the red blood ... three peripheral blood ... well as varying clinical ... majority of the leukocytes
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... Orange or Hep C Clinical ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... workup #oncology #hematology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... Abnormalities: macrocytic anemia ... (12%) • giant cell ... including peripheral blood ... Autoinflammatory #Somatic #rheumatology
Holistic Management of Systemic Lupus • Lifestyle interventions: Smoking cessation, Photoprotection, Therapeutic adherence, Anxiety/depression/fatigue, Fibromyagia/pain management,
Antimalarials for all ... • Blood/urine ... #holistic #SLE ... Systemic #Lupus #Erythematosus ... #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Clinical Domains ... least 2 joints • Neurologic ... pericarditis • Hematologic ... Classification #Criteria #SLE ... #diagnosis #rheumatology
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