21 results
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
RBC are produced ... Approximately 1% of RBC ... destruction of RBC ... 150,000 per mcL, and leukocytes ... majority of the leukocytes
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
peripheral blood leukocytes ... Even with normal WBC ... relative to both WBC ... bacteremia • Abnormal WBC ... diagnosis #neutrophil #WBC
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... #oncology #hematology ... #diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
• Blasts > 10% leukocytes ... Splenomegaly • ↑ Leukocyte ... - infiltrates (anemia ... AML Dx: • ↑ Leukocyte ... Leukemia #Hematology #Oncology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Autoimmune Hemolytic Anemia ... DIAGNOSE AIHA • Anemia ... ↑ LDH • Anti-RBC ... Autoimmune #Hemolytic #Anemia ... #diagnosis #management
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Diagnosis and Management ... hypercalcemia) • Anemia ... plus one of: • Anemia ... Myeloma #Diagnosis #Management ... #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... cytopenias (usually anemia ... acute leukemia Management ... MDS #Diagnosis #Management ... treatment #hematology #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Vmphocytosis on routine CBC ... 5) Symptoms of anemia ... marrow failure with anemia ... Lymphocytic #Leukemia #oncology ... hemeonc #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
if high risk if WBC ... QD until normal WBC ... APML #diagnosis #management ... #hematology #oncology
Chest Pain Diagnosis and Management Algorithm
STEMI:
 - Hx: Pressure like CP, Radiation to arm/jaw, CAD risk
Diagnosis and Management ... underlying dz (SLE, uremia ... friction rub, Fever, ↑WBC ... ChestPain #Diagnosis #Management