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rheumatology oncology causes disease workup approach joint msk pain abscess adultonset algorithm antibody arteritis autoimmune bandemia calculation cbc chronic cll
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... Blood Loss ... Deficiency • Aplastic ... #Classification ... #Causes #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Anemia: - Hepatitis ... anemia Treatment ... #hematology #diagnosis
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
↑ LDH • Anti-RBC ... type ± C3d • Blood ... smear: Differential ... #diagnosis #management ... #treatment #rheumatology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
the peripheral blood ... marrow failure: Aplastic ... Production #Index #hematology ... #anemia #differential ... #diagnosis #calculation
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
of peripheral blood ... leukocytes. ... cultures, including blood ... #differential # ... #WBC #CBC #hematology
Hepatobiliary Manifestations of Sickle Cell Disease Acute sickle cell hepatic crisis: • Fever, acute onset RUQ pain,
Supportive with treatment ... hepatomegaly and anemia ... Supportive with blood ... #hepatitis #differential ... #diagnosis
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
to Joint Pain - Diagnostic ... • Bloody: Trauma ... parvovirus, HIV, hepatitis ... approach #workup #differential ... #diagnosis #arthritis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... , erythema and WBC ... morning • Effusion leukocyte ... B19 • HIV • Hepatitis ... #Diagnosis #MSK
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Fever, Arthralgia/arthritis ... fraction < 20% Differential ... hepatomegaly, hepatitis ... #management #treatment ... #rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
• Aplastic Anemia ... factor (GCSF) treatments ... count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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