31 results
hematopoiesis - leukocyte maturation tree

- Amy Chung, MD, MSc @AmyChung 

#hematopoiesis #leukocytes #maturation #tree #pathophysiology #Hematology
hematopoiesis - leukocyte ... hematopoiesis #leukocytes ... pathophysiology #Hematology ... Progenitor #Cells #WBC
Gout Management in CKD
 • Colchicine
 • NSAID
 • Glucocorticoid
 • ACTH
 • Interleukin-1 Inhibitors

#Gout #Management
Management #CKD #rheumatology ... #treatment #comparison
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
peripheral blood leukocytes ... Even with normal WBC ... relative to both WBC ... 21% had normal WBC ... #CBC #hematology
Treatment of Latent Tuberculosis Infection
 - 3 mos isoniazid plus rifapentine given once weekly (Preferred)
 -
Treatment of Latent ... #Tuberculosis #treatment ... #management #infectiousdiseases ... #regimens #comparison
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
distinction has HUGE treatment ... and first-line treatment ... thrombocytopenia #Comparison ... Diagnosis #Table #Hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
↑ LDH • Anti-RBC ... diagnosis #management #treatment ... #rheumatology
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... RBC are produced ... destruction of RBC ... 150,000 per mcL, and leukocytes ... majority of the leukocytes
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Spherocytes • Treatment ... transient hemolysis • Treatment ... Hemolytic #Anemia #hematology ... #diagnosis #comparison
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... • Lab values: WBC ... organ damage • Treatment ... Low calcium • Treatment ... diagnosis #management #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Artifact (redo CBC ... effect following treatment ... Algorithm #Causes #Hematology