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Hyperkalemia Differential Diagnosis Algorithm R/O Pseudo-hyperkalemia: • Possible Lab error! Alwavs Repeat Blood sample! • Leukocytosis, Thrombocytosis:
• Leukocytosis, ... TTKG should be high ... causes #potassium #high
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Symptoms: • Daily high ... Lymphadenopathy • Leukocytosis ... Leukocytosis (10,000 ... • ↑ESR/CRP • Leukocytosis ... Plts • ↓Hgb • High
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Presentation: High ... , neutrophilic leukocytosis ... Systemic AOSD: high
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
thrombocytosis, leukocytosis ... phlebotomy High ... causes #potassium #high
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
thrombocytosis, leukocytosis ... phlebotomy High ... causes #potassium #high
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
• Attempt if high ... Diagnosis: • Labs: leukocytosis
Causes of Hyperkalemia - Differential Diagnosis Framework • Cellular Shift: - Exercise
Thrombocytosis, Leukocytosis ... Causes #potassium #high
Hyperkalemia Management Pseudohyperkalemia: 1. Hemolyzed sample 2. Blood drawn from a site/line where potassium or TPN is
thrombocytosis or leukocytosis ... treatment #potassium #high
Evaluation of Leukocytosis: The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages. Include
Evaluation of Leukocytosis ... In adults, leukocytosis ... LEUCOCYTOSIS WBC ... #LEUCOCYTOSIS #LEUKEMOIDREACTION
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Approach to Leukocytosis ... MatthewHoMD #Leukocytosis
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