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management hematology differential infectiousdiseases disease oncology pulmonary summary abscess causes hemophagocytic hlh lung lymphohistiocytosis american aplastic arthritis chagas chronic classification
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Hypothyroid • Liver ... #Macrocytic #Anemia ... #differential #diagnosis ... #algorithm #hematology ... #workup
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
Fever of Unknown ... Refer to your ‘Fever ... node biopsy • Clinical ... udaygulati #FUO #Fever ... #diagnosis
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Diagnosis: • Pancytopenia ... Treatment: • Consider ... if neutropenic fever ... #diagnosis #management ... #treatment #hematology
Lung Abscess Microbiology: • Polymicrobial • Anaerobes (most common) Clinical: • Indolent symptoms that evolve
Lung Abscess Microbiology ... most common) Clinical ... to rnonths • Fever ... , hemoptysis Treatment ... Lung #Abscess #Diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... Algorithm • Sickle ... bartonella (oroya fever ... #Algorithm #workup
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... for workup, including ... hemolysis, deficiency anemia ... Rebound effect from treatment ... #Algorithm #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... with leukopenia, anemia ... Treatment: • Corticosteroids
Hemophagocytic Lymphohistiocytosis (HLH) Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Lymphohistiocytosis (HLH) Clinical ... Features: Fever ... : ↑↑ ferritin, Anemia ... 8 criteria: • Fever ... #hematology #criteria
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... : • Fever • Fatigue ... index < 2 • EPO Level ... Treatment: ... #diagnosis #management
Oroya Fever Hematologic disease caused by Bartonella bacilliformis Restricted to the Andes highlands of Peru & Ecuador B. bacilliformis:
Oroya Fever Hematologic ... Inflammation: high fever ... severe hemolytic anemia ... TREATMENT: ​• Acute ... gabrieltalledop #Oroya #Fever
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