46 results
Complications of Measles: Pathogenesis and Clinical Findings
 • ADEM -> Fever, headache, neck stiffness, BBD, mental
Findings • ADEM -> Fever ... SOB, fatigue, fever ... N/V, elevated liver ... Complications #diagnosis #signs ... #symptoms #pathophysiology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... malaise) → Acute liver ... Transfer to a liver ... #AFLP #Fatty #Liver
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses
Medical History:
 • Skin exposure to
Regions - Frequent Differential ... localizing signs ... or symptoms - Malaria ... amebic abscess of liver ... or elevation of liver
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Pancreatitis - Elevated Liver ... Complications #pathophysiology ... #signs #symptoms
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
IBD • Chronic liver ... #Osteoporosis #pathophysiology ... #signs #symptoms
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Idiosyncratic Drug-induced Liver ... ongoing ↑ LFTs or symptoms ... of liver disease ... Drug #induced #Liver ... Idiosyncratic #differential
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... derangement of liver ... suspicious clinical symptoms ... /signs should be ... #Enzymes #Differential
Suspected Celiac Disease - Diagnosis Algorithm

Celiac disease suspected:
 • Signs and symptoms of celiac disease
 •
suspected: • Signs ... and symptoms of ... treatment • Elevated liver ... discernable cause • Signs ... microscopic colitis Differential
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone: • Liver ... activates lipolysis Signs ... /Symptoms: • GH ... endocrinology #pathophysiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... - 80% have fever ... WBC >100k, + lab signs ... TLS #diagnosis #management ... #hematology