19 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... diagnosis #management #hematology ... #oncology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
stratification algorithm ... for the treatment ... thrombosis; PE = pulmonary ... Anticoagulation #Management #Hematology ... #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... : Blast crises ... Headaches, bone pain, fever ... #Leukemia #Hematology ... #Oncology #Diagnosis
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... without other cause ... : 33% • Treatment ... , and CXR with pulmonary ... Transfusion #Reactions #hematology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... Treat underlying cause ... ICANS: altered level ... (~20 %) and APL ... renal failure, pulmonary
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... and petechiae Causes ... index < 2 • EPO Level ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
lung disease Caused ... shunt (Type 2) Clinical ... cirrhosis • Intra-pulmonary ... ) on room air Treatment ... #hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... DIC • Severe Liver ... Treat primary cause ... #treatment #management ... #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... microglobulin Treatment ... Transform to DLBCL, PML ... diagnosis #workup #oncology ... #hematology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
should be based on clinical ... Antimicrobial treatment ... status, and focal neurologic ... Demyelinating disease caused ... InfectiousDiseases #Neurology