89 results
Drugs and Classes Associated with DILI and Type of Liver Injury

#Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Drugs and Classes ... DILI and Type of Liver ... LiverInjury #Hepatology #Pharmacology ... #Causes #DILI
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
cause quadriplegia ... within GI and URT causes ... Maternal viremia causes ... > Inflammation causes ... peds #pediatrics #pathophysiology
Drugs that Cause Fever
Most commonly:
Amphotericin B, Antihistamines, Asparaginase, Barbiturates, Bleomycin sulfate, Methyldopa, Penicillins, Phenytoin sodium, Procainamide,
Drugs that Cause ... Fever Most commonly ... hydrochloride #Drug #Fever ... #causes #differential ... #diagnosis #pharmacology
Hydroxyurea - Pathophysiology and Benefits in Sickle Cell Disease
 • Decreases number of pain crises (
Hydroxyurea - Pathophysiology ... number of pain crises ... Benefits #SickleCell #pathophysiology ... #pharmacology
Oxyhemoglobin Dissociation Curve 

Left Shift - decreased unloading of O2 at tissue level (i.e.  increased
of O2 at tissue level ... of O2 at tissue level ... Dissociation #Curve #Pathophysiology ... #Differential #Causes
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... Pregnancy (AFLP) Pathophysiology ... hepatocytes → Liver ... = nonspecific (nausea ... diagnosis #management #pathophysiology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... agent • Does not cause ... m2 • Severe liver ... e.g. diarrhea, nausea ... #Metformin #Pharmacology
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Diarrhea, Insomnia, Nausea ... gain Incr NE: Nausea ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... #Pharmacology #
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Drug-induced edema is caused ... Edema #Medication #Causes ... #Differential #Pharmacology ... #Pathophysiology
Anaplasma Infection - Anaplasma phagocytophilum
Pathophysiology: 
 • Obligate, intracellular bacteria
 • Transmitted via blacklegged tick —
phagocytophilum Pathophysiology ... after bite • Fever ... is rare (< 10% cases ... ), cough (30% cases