34 results
diagnosis hematology syndrome hemophagocytic hlh lymphohistiocytosis classification comparison hemeonc hodgkins liver lymphoma mds myelodysplastic neurology pathophysiology workup abscess acidosis acromegaly
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... old, ~10,000 new cases ... only curative treatment ... #treatment #hematology ... #oncology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
syndromes Clinical ... is the main clinical ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... initiation • Differential ... Renal Failure Treatment ... APML #diagnosis #management ... #hematology #oncology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... infiltration) Differential ... Maternal Support - Critical ... #Pregnancy #hepatology ... obgyn #diagnosis #management
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Autoimmune diseases • Clinical ... involvement Differential ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Risk factors: Critical ... without other cause ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... triad: Fever, Arthralgia ... fraction < 20% Differential ... Disease #diagnosis #management ... #treatment #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... , ↓ Fibrinogen level ... Treatment: • ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... and petechiae Causes ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Portal venous gas on hepatic ultrasound: A concerning finding in the critically ill patient that should
reflection on the differential ... variety of other causes ... venousgas #ultrasound #hepatology ... #liver #pocus # ... clinical #air
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