73 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... , ↓ Fibrinogen level ... Treatment: • ... #summary #rheumatology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... without other cause ... ARDS to explain symptoms ... : 33% • Treatment ... #diagnosis #comparison
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... - 80% have fever ... Syndrome #TLS #diagnosis ... #management #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... = nonspecific (nausea ... Antithrombin Ill • Ultrasound ... ) Differential Diagnosis
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... and Management Summary ... survival is 93-95% Pathophysiology ... renal failure Clinical ... at the time of diagnosis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE) - Diagnosis ... and Management Summary ... 40, F:M 9:1 • Clinical ... life-threatening • Treatment ... #rheumatology
Pneumocystis jirovecii Pneumonia 
Clinical 
 • Caused by Pneumocystis jirovecii (formerly carinil) 
 • Immunocompromised host
jirovecii Pneumonia Clinical ... • Caused by ... CD4 < 200 • Symptoms ... often elevated Treatment ... PJP #Pneumonia #Diagnosis
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
and Management Summary ... extrapulmonary cases ... Clinical Signs ... decreased reflexes Pathophysiology ... #Management #Summary
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
Rheumatoid Arthritis Summary ... shoulders Signs & Symptoms ... narrowing) • Ultrasound ... Diagnosis: CLINICAL ... exam and imaging Treatment
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
and Management Summary ... • Most common cause ... Lung Abscess Pathophysiology ... Lung Abscess - Clinical ... decubitus - air fluid level