14 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
• Rheumatic fever ... Discoid skin lesions ... • Discoid lupus ... #rashes #differential ... #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Features of Systemic Lupus ... (SLE) General: Fever ... Cranial nerve lesions ... Abdominal pain ... symptoms #diagnosis #rheumatology
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Rheumatica • Pain ... proximal joints, Fever ... Diffuse muscle pain ... Myopathies #myopathy #differential ... diagnosis #comparison #rheumatology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
Inflammatory joint pain ... and fingers, or pain ... the face (many differential ... 9) Unexplained fever ... erythematosus #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... reddish-purple lesions ... • Severe pain ... Autoimmune Vasculitis (lupus ... deficiency Work
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
papulosquamous lesions ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... Arthritis: • Joint pain ... Erythematosus #Diagnosis #Rheumatology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
patients Skin lesions ... symptoms - Headache, fever ... Nausea, abdominal pain ... Urticaria #diagnosis #rheumatology ... #comparison #table
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... , and low back pain ... Arthritis #laboratory #workup ... diagnosis #testing #Rheumatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Approach to Joint Pain ... spondyloarthropathies, lupus ... #rheumatology # ... approach #workup ... #differential #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... ischemic skin lesions ... inflammation Others: • Lupus ... such as systemic lupus ... #diagnosis #rheumatology