13 results
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Rheumatica • Pain ... proximal joints, Fever ... Diffuse muscle pain ... Myopathies #myopathy #differential ... diagnosis #comparison #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Features of Systemic Lupus ... (SLE) General: Fever ... Abdominal pain ... Glomerulonephritis Myositis ... symptoms #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
• Rheumatic fever ... Discoid skin lesions ... • Discoid lupus ... #rashes #differential ... #diagnosis #rheumatology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
patients Skin lesions ... symptoms - Headache, fever ... Nausea, abdominal pain ... Urticaria #diagnosis #rheumatology ... #comparison #table
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
- Differential ... continence • Pain ... reported at level ... loss: Sensory level ... #differential
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
or without back pain ... at/near level of ... lesion • Bilateral ... defined sensory level ... #differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
papulosquamous lesions ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... Arthritis: • Joint pain ... Erythematosus #Diagnosis #Rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... reddish-purple lesions ... • Severe pain ... Autoimmune Vasculitis (lupus ... deficiency Work
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... to exclude myositis ... , and low back pain ... diagnosis #testing #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... ischemic skin lesions ... inflammation Others: • Lupus ... such as systemic lupus ... #diagnosis #rheumatology