126 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
deficiency • Liver ... mountain spotted fever ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Kerion
Raised, boggy lesion with heaped up purulent nodules 
Caused by host's response to a fungal ringworm
purulent nodules Caused ... Hair loss • Fever ... Griseofulvin #Kerion #Dermatology ... #Diagnosis #Management
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Evaluation and Management ... of Sickle Cell Crises ... Manifestations and Management ... #Diagnosis #Management ... #Hematology #SickleCell
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... ALT ↑ bilirubin level ... #Hematology #Rheumatology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
if neutropenic fever ... Anemia #diagnosis #management ... #treatment #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Renal Disease, Liver ... Reticulocytosis • Liver ... Diagnosis #Algorithm #Causes ... #Hematology
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
Fever vs Hyperthermia ... Fever: • Regulated ... rapidly fatal • Causes ... BrighamChiefs #Fever ... comparison #diagnosis #management
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... : INR/PT, aPTT(liver ... bypass), LFT (liver ... patients if the cause ... #Workup #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion
Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Clinical Features: Fever ... 8 criteria: • Fever ... Lymphohistiocytosis #diagnosis #hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Anemia Intrinsic Causes ... elliptocytosis Extrinsic Causes ... : • Liver disease ... Intravascular Causes ... classification #hematology