61 results
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
hepatic crisis: • Fever ... Supportive with blood ... cholestasis: • Fever ... liver failure ... Liver transplant
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
HELLP Syndrome and Acute ... Fatty Liver of ... Hemolysis, Elevated Liver ... exchange 3) Fatty liver ... #obstetrics #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... liver failure rapidly ... Transfer to a liver ... #Fatty #Liver #
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... Liver Failure ( ... intestines, White blood ... #chemistry #diagnosis ... #differential #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Algorithm Vascular Causes ... of Acute Liver ... intestines, white blood ... #algorithm #hepatology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Hemolysis, Elevated Liver ... exchange 2) Fatty liver ... coagulation defects and liver ... TTPHUS #HELLP #AFLP ... Obstetrics #OBGyn #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
plateletcount), peripheral blood ... : INR/PT, aPTT(liver ... bypass), LFT (liver ... #Causes #Workup ... #hematology
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... Non-Infectious Causes ... Brucellosis Faget's Sign ... Brucellosis • Liver ... #Differential #Diagnosis
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Algorithm Normal Blood ... WBCs - Normal Liver ... Deficiency - Abnormal Liver ... Tests • Liver ... #Hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... if neutropenic fever ... progress to MDS or acute ... #management #treatment ... #hematology