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management differential symptoms hematology causes disease erythematosus lupus pocus sle systemic algorithm arteritis comparison criteria dermatology hemophagocytic hlh hodgkins infections
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... (SLE) General: Fever ... Butterfly rash, Vasculitis ... erythematosus #signs ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Coronary arteries - Fever ... : • Fevers • ... purpura: strong sign ... #rheumatology # ... classification
Sarcoidosis Non-caseating granulomas (Composed of T-helper & inflammatory cells) Clinical: • Disease fatal in 10% of
inflammatory cells) Clinical ... Constitutional: Fever ... exertion • Neurologic ... #Sarcoidosis #Diagnosis ... #Symptoms #Signs
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Erythematosus Clinical ... Constitutional domain: Fever ... least 2 joints • Neurologic ... Erythematosus #diagnosis ... #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Hyperthyroidism Fever ... • Rheumatic fever ... SLE, Rheumatic fever ... • New murmur, fever ... #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... and branches • Fever ... affects the skin, neurologic ... Coronary arteries • Fever ... #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... Labs/Diagnosis: ... C4 complement level ... #types #classification ... #rheumatology #
Lyme Disease: Early and Late Clinical manifestations Stage 1. Localized • EM appears 7-14 days at the
Early and Late Clinical ... arthralgia, headache, fever ... • Heralded by neurologic ... Lyme #Disease #diagnosis ... #signs #symptoms
Emphysematous Cystitis Epidemiology: • Usually middle-aged diabetic women • Other RF: neurogenic bladder, urinary tract outlet obstruction,
immune compromise Clinical ... Signs/Symptoms: ... cystitis, may have fever ... infection, such as fever ... KUB or abdominal ultrasound
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Infection - Vasculitis ... Red Flags: • Fever ... blood test • Serology ... • Abdominal ultrasound
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