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diagnosis management hematology pain oncology arthritis classification cppd disease erythematosus gout hodgkins infectiousdiseases lupus lymphoma msk myopathy myositis sle vasculitis
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
acute rheumatic fever ... infection. ... #rheumatology # ... approach #workup ... #differential #
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
, Fever, No muscle ... myopathy) VA Joint ... Myopathies #myopathy #differential ... #diagnosis #comparison ... #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Hyperthyroidism Fever ... • Rheumatic fever ... SLE, Rheumatic fever ... • New murmur, fever ... #pain #differential
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Pain - Arthritis Differential ... - Autoimmune Rheumatologic ... • Rheumatic fever ... streptococci (rheumatic fever ... #pain #Differential
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... parvovirus B19 infection ... • Rheumatic fever ... #skin #rashes #differential ... #diagnosis #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... fraction < 20% Differential ... Diaqnoses: • Infectious ... diagnosis #management #treatment ... #rheumatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Non-Hodgkin's Lymphoma - Comparison ... e.g., HIV), EBV infection ... - Pel-Ebstein fever ... Etiology: - Infections ... #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... inclusions - If infection ... bartonella (oroya fever ... Diagnosis #Algorithm #workup ... #hematology #testing
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
respiratory symptoms • Fever ... pulmonary symptoms • Rheumatologic ... • Cough, fever ... muscle aches, joint ... • Isolated fever
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
) Inflammatory joint ... the face (many differential ... 9) Unexplained fever ... , when infection ... erythematosus #rheumatology
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