128 results
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Malar rash 40% - Fever ... (aPL) 30-45% Differential ... Diagnosis and Lupus ... autoantibodies #signs ... #rheumatology
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis
 • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Causes of Fever ... Brucellosis, Q fever ... . autoimmune): Lupus ... Mediterranean fever ... , Factitious fever
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
inflammatory cells) Clinical ... : • Disease fatal ... Constitutional: Fever ... exertion • Neurologic ... #Symptoms #Signs
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... • Rickettsial diseases ... Brucellosis Faget's Sign ... #Patterns #Differential ... #Diagnosis #intermittent
Acute Fever in-from the Tropics - Clinical Examination

#Tropics #Traveler #Fever #Differential #Signs #Diagnosis #InfectiousDiseases
Acute Fever in-from ... the Tropics - Clinical ... Tropics #Traveler #Fever ... #Differential # ... Signs #Diagnosis
Faget's Sign & Liebermeister's Rule
Pulse-Temperature Dissociation
EVERY 1 F RISE IN TEMPERATURE -> HR INCREASES 8-10 BPM
INFECTIOUS
Faget's Sign & Liebermeister's ... CLINICAL UTILITY ... #Fagets #Sign #Pulse ... #Dissociation #diagnosis ... #differential #
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... (SLE) General: Fever ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... ALT ↑ bilirubin level ... Activation #Syndrome #Diagnosis
Inflammatory Joint Pain - Differential Diagnosis Algorithm 
Monoarticular
 • Gout (Podagra, Tophi)
 • Pseudogout
 • Early
Inflammatory Joint Pain - Differential ... Diagnosis Algorithm ... • Rheumatic Fever ... Arthritis • Systemic Lupus ... • Rheumatic Fever
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
or absence of fever ... If fever is present ... Kawasaki disease ... , scarlet fever, ... but without a fever