12 results
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
, Fever, No muscle ... uncommon 5-15% of lupus ... myopathy) VA Joint ... #differential # ... diagnosis #comparison #rheumatology
Inflammatory Joint Pain - Differential Diagnosis Algorithm 
Monoarticular
 • Gout (Podagra, Tophi)
 • Pseudogout
 • Early
Pain - Differential ... Diagnosis Algorithm ... • Rheumatic Fever ... Arthritis • Systemic Lupus ... • Rheumatic Fever
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
acute rheumatic fever ... spondyloarthropathies, lupus ... #rheumatology # ... approach #workup ... #differential #
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... • Rheumatic fever ... lesions • Discoid lupus ... #skin #rashes #differential ... #diagnosis #rheumatology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... ) Inflammatory joint ... the face (many differential ... 9) Unexplained fever ... erythematosus #rheumatology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Diagnosis Algorithm ... bartonella (oroya fever ... #Diagnosis #Algorithm ... #workup #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... permanent alopecia Differential ... Arthritis: • Joint ... arthropathy • 90% joints ... to: Arthritis, Fever
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Diagnosis Algorithm ... Red Flags: • Fever ... Autoimmune Vasculitis (lupus ... deficiency Work ... • Abdominal ultrasound
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm
Structural Defect - Asplenia/HypospIenism
 • Bacteremia/Septic
Causes of Fever ... Diagnosis Algorithm ... Infection • Abscess ... Infection #Fever ... #Causes #Hematology
Causes of Cystic Renal Mass - Differential Diagnosis Algorithm
Benign - Anechoic on ultrasound, Well-demarcated on ultrasound/CT,
Cystic Renal Mass - Differential ... Diagnosis Algorithm ... Carcinoma - Abscess ... - Fever and leukocytosis ... #Diagnosis #Algorithm