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diagnosis hematology oncology causes management algorithm aplastic cardiology classification hemolytic hodgkins lymphoma pericardial acidosis apml bandemia cbc chronic cll comparison
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Hypothyroid • Liver ... #Macrocytic #Anemia ... #differential # ... diagnosis #algorithm #hematology ... #workup
Causes of Pericardial Effusion - Differential Diagnosis Infectious: • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus • Bacterial: Mycobacterium
of Pericardial Effusion ... - Differential ... Non-Infectious: • Rheumatologic ... Mediterranean Fever ... Primary: Lymphoma, Leukemia
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... • Symptomatic anemia ... if neutropenic fever ... to MDS or acute leukemia ... management #treatment #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... Extrinsic Causes: • Liver ... #Differential # ... classification #hematology
Hemorrhagic Pericardial Effusions (Hemopericardium)- Differential Diagnosis Framework IATROGENIC DISEASE Secondary to invasive cardiac procedures NONIATROGENIC • Malignancy (e.g., metastatic spread:
Hemopericardium)- Differential ... cancer, lymphoma, leukemia ... amyloidosis • Uremia ... Mediterranean fever ... Hemopericardium #Differential
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... bartonella (oroya fever ... Diagnosis #Algorithm #workup ... #hematology #testing
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... Headaches, bone pain, fever ... - infiltrates (anemia ... Lymphadenopathy • HSM • Fevers ... #Hematology #Oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Presentation: • Fever ... recurrent infections/fevers ... virus (EBV) • Leukemia ... index < 2 • EPO Level ... #oncology #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... Lymphadenopathy • Fevers ... • Neutropenia, anemia ... #diagnosis #workup ... #oncology #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - Hemolytic anemia ... mountain spotted fever ... #Diagnosis #hematology ... #rheumatology #
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