314 results
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
hepatic crisis: • Fever ... Supportive with treatment ... cholestasis: • Fever ... Hepatobiliary #hepatology ... #differential #diagnosis
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Purpura (TTP) Diagnosis ... soon as TTP is diagnosed ... PLEX and RTX • Short-term ... #rheumatology # ... hematology
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
suspect underlying hematologic ... disorders • Diagnosis ... and Treatment Algorithm ... Syndrome #HES #Hematology ... #eosinophils #diagnosis
Differential Diagnosis - Fever of Unknown Origin (FUO)

IMADE mnemonic:
 • Infection
 • Malignancy
 • Autoimmune (Rheumatologic)
Differential Diagnosis ... - Fever of Unknown ... • Autoimmune (Rheumatologic ... udaygulati #FUO #Fever ... #diagnosis #IMADE
Temporal (Giant cell) Arteritis 
Risk Factors:
 • Age (almost never occurs before age 50) 
Clinical:
 •
• Age (almost never ... GiantCell #Arteritis #Diagnosis ... #Rheumatology #
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Symptomatic anemia Diagnosis ... megaloblastic anemia Treatment ... if neutropenic fever ... #management #treatment ... #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... #Management #Hematology ... #Rheumatology
Adult Onset Still's Disease - Yamaguchi Criteria
Major criteria:
 - Fever >= 39C lasting >= 1 weeks
criteria: - Fever ... with concomitant fever ... Abnormalities in liver ... Yamaguchi #Criteria #Diagnosis ... #Major #Minor #Rheumatology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
: High spiking fever ... Systemic AOSD: high fever ... synovitis (40%) Treatment ... Disease #AOSD #rheumatology ... #treatment
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
Fever of Unknown ... Refer to your ‘Fever ... values supporting hematologic ... udaygulati #FUO #Fever ... UnknownOrigin #workup #diagnosis