55 results
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
Fever of Unknown ... • CNS symptoms ... Refer to your ‘Fever ... Returning Traveler’ algorithm ... udaygulati #FUO #Fever
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
Hypothyroid • Liver ... differential #diagnosis #algorithm ... #hematology #workup
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... ALT ↑ bilirubin level ... Diagnosis #Management #Hematology
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
Algorithm for workup ... hemolytic uremic syndrome ... thrombocytopenia, Hematology ... #Differential #Algorithm
Diagnostic criteria for Neutropenic Enterocolitis (NEC)
Major Criteria:
 • Neutropenia (ANC <500 x 10^9 cells/L)
 • Bowel
Diagnostic criteria ... Enterocolitis (NEC) Major Criteria ... 30mm length) • Fever ... >38.3°) Minor Criteria ... #hematology #oncology
Hemophagocytic Lymphohistiocytosis (HLH)
Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion
Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Clinical Features: Fever ... the following 8 criteria ... : • Fever • Splenomegaly ... Lymphohistiocytosis #diagnosis #hematology ... #criteria
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
: ARDS Berlin Criteria ... ARDS to explain symptoms ... • Fever and hypotension ... pulmonary edema) • Fever ... Transfusion #Reactions #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome ... #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... Differential Diagnosis Algorithm ... HLH syndrome 5. ... #Pancytopenia #Workup ... #Hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... evaluation or workup ... for specific symptoms ... 1,500 cells/µL Workup ... Differential #diagnosis #hematology