26 results
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Malar rash 40% - Fever ... involvement 3% SLE-Related ... Lupusreference #SLE ... autoantibodies #signs ... #differential #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Malar rash • SLE ... • Rheumatic fever ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... differential #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(SLE) General: ... Fever (50%), Depression ... pain (20%) Renal disease ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Associated - SLE ... mountain spotted fever ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms
Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
(SLE) - Typical ... Signs/Symptoms ... Alopecia, Fever, ... #Signs #Symptoms ... #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... Diagnosis #Management #Hematology ... #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... weight loss, and fever ... Erythematous, macular ... Non-autoimmune rheumatologic ... to: Arthritis, Fever
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis
Malar rash: 
 • A
and Arthritis in Pediatrics ... Suggestive of: Rheum Fever ... migrans: • Target sign ... gabrieltalledop #dermatology ... diagnosis #peds #pediatrics
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
9) Unexplained fever ... including in children (pediatric ... SLE) 10) When ... #diagnosis #sle ... erythematosus #rheumatology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Consider sickle cell disease ... ): SS, SC, SE, Sβ ... , Hemoglobin H disease ... bartonella (oroya fever ... Algorithm #workup #hematology