26 results
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Presentation: • Fever ... index < 2 • EPO Level ... Treatment: ... #oncology #hematology ... #diagnosis #management
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Neutropenic fever ... : - Fever + ANC ... interventional radiology ... or HSCT - CRS: fever ... therapy - Symptoms: fever
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Subacute-Acute: • Common: fever ... common • Imaging: CXR ... - pulmonary opacities ... APML #diagnosis #management ... #hematology #oncology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... with leukopenia, anemia ... #Diagnosis #Management
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
: • 80% have fever ... Leukocytosis, anemia ... Blood cultures • CXR ... early disease) • CXR ... Lung #Abscess #pulmonary
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
, dyspnea, +/- CXR ... - 80% have fever ... organ damage • Treatment ... acid, Elevated Cr ... TLS #diagnosis #management
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... e.g. incidental CXR ... General: fever, ... : ACUTE, fever, ... presentation with fever
Visceral Leishmaniasis - Diagnosis and Management Summary
Species: Leishmania donovani, Leishmania infantum, Leishmania chagasi
Where: South Asia, East
Diagnosis and Management ... 2-6 months • Fever ... Lymphohistiocytosis • Anemia ... Bilirubin, ↑BUN/Cr ... culture, PCR, K39) Treatment
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
Diagnosis and Management ... active ROM +/- fever ... arthritis diagnosis Treatment ... 90% sensitive in pediatrics ... cervical, anal Cxs
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary
Clinical features - Classic triad (flank pain, hematuria,
Diagnosis and Management ... Anemia (common) ... night sweats, fever ... Budd Chiari syndrome ... disease Imaging and Treatment