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diagnosis hematology management cardiology differential lupus sle systemic activation acute aplastic causes criteria dermatology dermatosis effusion endocarditis febrile hemeonc hemophagocytic
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... with leukopenia, anemia ... Treatment: • Corticosteroids
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
(SLE) General: Fever ... Demyelinating syndromes ... ) Blood (75%): Anemia ... SLE #systemic #erythematosus ... symptoms #diagnosis #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Presentation: • Fever ... recurrent infections/fevers ... index < 2 • EPO Level ... Treatment: ... #oncology #hematology
Causes of Pericardial Effusion - Differential Diagnosis Infectious: • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus • Bacterial: Mycobacterium
Non-Infectious: • Rheumatologic ... Mediterranean Fever ... Disease, Behcet Syndrome ... • Metabolic: Uremia ... Diagnosis #Causes #cardiology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... Non-autoimmune rheumatologic ... lymphopenia, low PLT • Anemia ... to: Arthritis, Fever ... #Diagnosis #Rheumatology
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis) Major criteria 1. Abrupt onset of tender
Criteria for Sweet Syndrome ... onset of tender erythematous ... Fever, temperature ... Excellent response to treatment ... Criteria #Diagnosis #Hematology
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
- Anasarca - Fever ... systemic lupus erythematosus ... disease, severe fever ... Hypoalbuminemia Treatment ... diagnosis #management #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Characteristics: Persistent fever ... Persistent high fever ... - Cytopenias (anemia ... Fever b. ... Diagnosis #Management #Hematology
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
night sweats, fever ... Cholesterol emboli syndrome ... Leukocytosis, anemia ... hematuria, + RF Treatment ... Persistent bacteremia/fevers
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